GONADORELIN PEPTIDE 2MG/5MG VIAL
$25.99 – $54.99
Gonadorelin is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.
- Description
- Additional information
Description
Gonadorelin Peptide
CAS Number | 33515-09-2 |
Other Names | GONADORELIN, Dirigestran, Lutrefact, Relefact, Luforan, Lutamin, Lutal, Relisorm l, Synthetic LRF, Dirigestran Spofa |
IUPAC Name | N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide |
Molecular Formula | C₅₅H₇₅N₁₇O₁₃ |
Molecular Weight | 1182.3 |
Purity | ≥99% Pure (LC-MS) |
Material Safety Data Sheet (MSDS) | |
Liquid Availability | N/A |
Powder Availability | |
Storage Condition | Store cold, keep refrigerated. Do NOT freeze. |
Terms | All products are for laboratory developmental research USE ONLY. Products are not for human consumption. |
**Important Information: Each peptide comes lyophilized/freeze-dried and must be reconstituted with Bacteriostatic Water in order to be dispensable in liquid form.
Watch How To Reconstitute Peptide Video HereGonadorelin is a peptide that is similar to gonadotropin-releasing hormone (GnRH). GnRH is naturally made and released from the hypothalamus while gonadorelin is an injection that has been tested in cattle and rats. Gonadorelin has been shown to play a large role in the regulation of the reproductive system through the hypothalamus-pituitary gonadal (HPG) axis. When gonadorelin is administered it leads to the release of luteinizing hormone (LH) and follicle-stimulating hormone, which in turn, regulate the reproductive system in both males and females.
Effects of Gonadorelin on the Release of Luteinizing Hormone
In a study conducted by Martinez et. Al, three different variations of gonadorelin were given to cows in order to observe how the peptide would affect various follicular dynamics as well as the release of luteinizing hormone. Gonadorelin was formulated into three different variations for the sake of this study. In the preliminary experiment, nonlactating Holstein cows were randomly chosen to be given an intramuscular injection of gonadorelin diacetate tetrahydrate, the two forms being, Cytorelin (C) and Fertagyl (Fe). The cows then got their blood drawn for an LH analysis at 0, 1, 2, and 4 hours after injection in order to prepare for the second experiment.
In the second experiment, nonlactating Holstein cows were randomly chosen to be given injections of either Cytorelin, Fertagyl, or Factrel (FA, gonadorelin hydrochloride). The injection was given to the cows 6 to 7 days after their ovulation period and from there, an LH analysis was done 0,1, 2, 4, and 6 hours after treatment, and sonograms were performed twice a day to check for ovulation.
Following the second experiment, a third experiment was conducted with young, female beef cows where they were randomly selected to receive 1 of 3 of the gonadorelin formulation. From there the researchers waited 6 to 7 days after ovulation and took blood samples for LH analysis at hours 0, 0.5, 1, 1.5, 2, and 4 as well as sonograms of the ovaries.
Results of this study showed that in experiments 2 and 3, the Holstein cows treated with Cytorelin had higher mean and mean peak plasma LH concentrations. Furthermore, the Holstein cows treated with Cytorelin had a higher number of dominant follicles in an ovulation period than those treated with Fertagyl or Factrel. However, treatment with C versus FE or FA had an unremarkable effect on the beef heifers. Therefore, the study concluded that Cytorelin had the greatest effect on LH release (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC340045/).
Peptides Prefer the Cold
In order to reduce peptide breakdown, keep peptides refrigerated at all times but DO NOT FREEZE.
Swab the top of the vial with 95% alcohol wipe before accessing.
Only Mix with Sterile Bacteriostatic Water
Bacteriostatic water is vital to preventing contamination and preserving the stability of the compound.
Push the pin through the stopper at an angle in order to direct the stream to the side of the vial.
Reconstituted peptide solution should be stored at around 4 degrees Celsius but not frozen, while lyophilized peptide solution should be kept at -20 degrees Celsius.
Gonadorelin is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.
File Name | View/Download |
2024-09-17-Umbrella-Labs-Gonadorelin-Certificate-Of-Analysis-COA.pdf |
VIEW CERTIFICATES OF ANALYSIS (COA)
Additional information
Weight | 1 oz |
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Dimensions | 0.5 × 0.5 × 1 in |
Molar Mass | 1182.3 g·mol−1 |
CAS Number | |
Molecular formula | C55H75N17O13 |
Size |