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5-Alpha-Hydroxy Laxogenin Information



Molecular Formula C₂₇H₄₂O₅
Molecular Weight 446.6
Purity ≥99% Pure (LC-MS)
Storage Store in cool dry environment, away from direct sunlight.
Terms Lab Use Only. This information is for educational purposes only and does not constitute medical advice.

Shipping Conditions: Ambient temperature.


5-alpha hydroxy laxogenin is a plant-derived polyhydroxylated derivative of 5a-cholestane, similar to anabolic steroids in mammals or insect ecdysteroids. that is derived from the compound laxogenin. Studies show that 5-alpha hydroxy laxogenin acts as an alternative option to anabolic steroids. Laxogenin belongs to a family of compounds called brassinosteroids. Furthermore, studies also show that laxogenin is found throughout the structure of the plant and has been known to drive the growth of the plant. 


A fascinating experiment conducted by Esposito et. Al studies the effects that a similar compound, 28-Homobrassinolide (HB) has on the lean body mass of test rodents. Over a 24 day period rodents were given doses of either 20 mg or 60 mg. Through the use of a DEXA scan, it was found that the group of rodents being treated with 20 mg had a 7% increase in lean muscle mass while the group being treated with 60 mg had a 14.2% increase in lean muscle mass. Additionally, the 20 mg treatment group lost 3.9% body fat while the 60 mg group had a 4.9% reduction in body fat. HB treatment was also associated with an increase in strength without additional training, as the rats exhibited a 6.7 percent increase in grip strength of the lower extremities. 





As it was previously mentioned, laxogenin belongs to a family of compounds referred to as brassinosteroids. Brassinosteroids are a phytohormone that has a crucial role in plant development and growth. Brassinosteroids have many similarities to animal hormones as they both play crucial roles in various growth methods such as cell elongation and division, as well as being involved in the reproductive and immune systems (https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0340-8).


5-Alpha Hydroxy Laxogenin Effects on Protein Synthesis

There are many avenues of research available for 5-Alpha hydroxy laxogenin, and at this time, there is a paucity of studies available. Theoretically, however, it may be that supplementation leads to an increase in the rate of protein synthesis while also leading to a decrease in protein breakdown.


5-Alpha Hydroxy Laxogenin Effects of Hormones 

Supplementation with SARMs frequently leads to changes in hormone levels. 5-alpha hydroxy laxogenin is unique since there are no reported changes to the hypothalamic-pituitary-testicular axis (HPTA). In the study conducted by Esposito et. Al, it was found that when treating with HB there was no reported occurrence of binding to the androgen receptor.


5-Alpha Hydroxy Laxogenin Availability 

We find many researchers prefer flexibility in their compounds and we are proud to offer 2 different formulations that will meet your research needs: powdered and poly-cell. Our powdered formulation is ideal for researchers who wish to have the flexibility to reconstitute the compound in the diluent that best suits their research goals. 


The primary concern for SARM researchers today is where to buy SARMS that are reliable and consistently pure. Umbrella Labs insures and guarantees its product purity by incorporating a process of Independent testing using Mass Spectrometry and Ultraviolet Radiation. Certificates of our product Independent tests are posted with our product descriptions.



*The information herein is for educational and informational purposes only. THIS PRODUCT IS FOR RESEARCH USE ONLY. For use in animal studies, all research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).


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Additional information

Weight 2 oz
Dimensions 3 × 3 × 5 in
PubChem CID

Molar Mass

446.6 g·mol−1

Molecular Formula