ACP-105 SARM POWDER – 1000MG / 1 GRAM

$87.99

Only 9 left in stock

Only 9 left in stock

ACP-105

ACP-105 was one of the first SARMs to be developed using the proprietary Receptor Selection and Amplification TechnologyTM (R-SAT). R-SAT is a functional cell-based assay that allows the monitoring of receptor-dependent proliferative responses of various receptor classes, including G-protein-coupled receptors and nuclear receptors like the Androgen Receptor (AR).

 

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).

References

  1. N. Schlienger et al., “Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators,” J. Med. Chem., 2009.
  2. C. A. Frye, K. Edinger, and K. Sumida, “Androgen administration to aged male mice increases anti-anxiety behavior and enhances cognitive performance,” Neuropsychopharmacology, 2008.
  3. M. Ramsden et al., “Androgens modulate β-amyloid levels in male rat brain,” J. Neurochem., 2003.
  4. S. Acevedo, L. Gardell, S. Bradley, F. Piu, and J. Raber, “Selective Androgen Receptor Modulators Antagonize Apolipoprotein E4-Induced Cognitive Impairments,” Lett. Drug Des. Discov., 2008.
  5. C. Dayger, L. Villasana, T. Pfankuch, M. Davis, and J. Raber, “Effects of the SARM ACP-105 on rotorod performance and cued fear conditioning in sham-irradiated and irradiated female mice,” Brain Res., 2011.
  6. E. Nieschlag, “Testosterone treatment comes of age: New options for hypogonadal men,” Clinical Endocrinology. 2006.
  7. S. Basaria and A. S. Dobs, “Risks versus benefits of testosterone therapy in elderly men,” Drugs and Aging. 1999.
  8. R. W. Mahley, “Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology,” Science. 1988.
  9. Y. Huang, “Molecular and cellular mechanisms of apolipoprotein E4 neurotoxicity and potential therapeutic strategies,” Current Opinion in Drug Discovery and Development. 2006.
  10. F. Berteau-Pavy, B. Park, and J. Raber, “Effects of sex and APOE ε4 on object recognition and spatial navigation in the elderly,” Neuroscience, 2007.
  11. D. M. Martin, G. Wittert, N. R. Burns, M. T. Haren, and R. Sugarman, “Testosterone and cognitive function in ageing men: Data from the Florey Adelaide Male Ageing Study (FAMAS),” Maturitas, 2007.
  12. E. R. Rosario, J. C. Carroll, S. Oddo, F. M. LaFerla, and C. J. Pike, “Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer’s disease,” J. Neurosci., 2006.

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Additional information

Weight 2 oz
Dimensions 3 × 3 × 5 in
CAS Number‎

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