L-TYROSINE POWDER (100 GRAMS)
L-Tyrosine is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.
- Additional information
L-Tyrosine Nootropic Powder
|Other Names||Tyrosine, 60-18-4, (S)-Tyrosine, p-Tyrosine, L-p-Tyrosine, H-Tyr-OH|
|IUPAC Name||(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid|
|Purity||≥99% Pure (LC-MS)|
|Powder Availability||100 grams|
|Storage||Store in a dry, cool, dark place. For best preservation, store at 4°C or colder away from bright light.|
|Terms||All products are for laboratory developmental research USE ONLY. Products are not for human consumption.|
Benefits of L-tyrosine
L-tyrosine is a nonessential amino acid that produces two main catecholamines, dopamine and norepinephrine. These two compounds are typically depleted in instances of chronic stress. However, evidence has found that supplementation of L-tyrosine helps to replenish dopamine and norepinephrine which has shown to have beneficial effects on cognition, such as memory, attention, and performance levels in stressful situations.
Initial studies regarding the effectiveness of L-tyrosine against stress were conducted on rats. The rats were subjected to extreme cold in order to simulate environmental stress. This led to a dramatic decrease in their memory due to the depletion of catecholamines. However, after being administered L-tyrosine their memory was quickly restored. L-tyrosine was also found to improve working memory and cognitive flexibility, or the ability to quickly switch from one task to another. In a group of 22 subjects, the animals were given either a placebo or a dose of L-tyrosine. Compared to the placebo group there was a drastic difference in working memory and cognitive flexibility, both of which were tested by various field tests.
L-tyrosine has also shown potential in combating sleep disorders. The compound was administered to animals completing 24 hours of performance tasks in order to induce sleep deprivation. A 150 mg/kg dose was given to half of the subjects after 6 hours of work while the other half received a placebo. The study found that in comparison with the placebo, L-tyrosine led to a significant improvement in the subjects’ performance on the measured tasks despite the sleep deprivation. Additionally, the single dose of L-tyrosine was shown to allow the subjects to sleep for approximately 3 hours longer than normal following their night of sleep deprivation. Different doses of the compound were also tested and found to have similar effects on sleep quality and performance levels (https://pubmed.ncbi.nlm.nih.gov/7794222/).
Another interesting benefit of L-tyrosine supplementation is its ability to help treat the condition phenylketonuria (PKU). PKU is a genetic disorder that doesn’t allow for the synthesization of the enzyme phenylalanine hydroxylase, which allows for phenylalanine to be broken down into tyrosine. Without this enzyme phenylalanine builds up in the body causing negative side effects. The primary treatment for PKU is eliminating foods with phenylalanine, however, this can cause tyrosine deficiency and lead to behavioral problems associated with depleted catecholamines. That being said, supplementing with L-tyrosine can lead to the resolution of behavioral problems as well as an improvement in cognition and overall quality of life. However, some results regarding this form of treatment have been labeled as inconclusive which indicates that further research needs to be conducted (https://www.healthline.com/nutrition/tyrosine#TOC_TITLE_HDR_4).
Effects of L-tyrosine on Acute Stress
While traditional treatments and medications for stress are quite effective they tend to come with side effects that are not frequently seen in alternative methods. Researchers Lieberman et. Al cited many studies regarding the efficacy of using L-tyrosine to combat acute stress. The most notable study induced acute stress onto rats through a 60 minute long tailshock. The animals were given 15 minutes to recover and then placed in an open-field apparatus while their spontaneous behavior was observed. Following this test the brains of the rats were removed and examined. Researchers found that this level of stress reduced locomotor activity and spontaneous behavior by 80%. This control group was compared to the experimental group of rats that received a diet high in tyrosine. Results found that while there was no drastic difference in spontaneous behavior, but the added tyrosine protected the rats from behavioral inhibition, most likely due to the increase in catecholamines.
A similar study was conducted where the rats underwent tailshock stress and then were immediately given an intraperitoneal injection of a 200 mg/kg dose of L-tyrosine or a placebo. The results of the study showed that in the animals that were given a placebo, there was a 30-40% decrease in norepinephrine throughout the brain. However, in the rats injected with L-tyrosine this depletion was avoided and the turnover rate of norepinephrine increased. Additional studies subjected the rats to extreme cold and examined changes in the subjects mobility. Overall results found that mobility and activity levels drastically decreased in placebo-treated animals during this kind of acute stress. However, the subjects treated with L-tyrosine were able to maintain normal performance levels despite the stressor (https://www.ncbi.nlm.nih.gov/books/NBK209061/).
The nootropics sold by Umbrella Labs are sold for laboratory research only. The description above is not medical advice and is for informative purposes only.
|Dimensions||0.5 × 0.5 × 1 in|