RAD-150 (TLB 150) SARM – 20MG/ML – 30ML/60ML BOTTLE


Rad-150 SARM is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.

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RAD-150 (aka TLB-150 or RAD-140 Ester)



Molecular Formula C₁₆H₂₅ClN₂O
Molecular Weight 296.83
Purity ≥99% Pure (LC-MS)
Storage Store in cool dry environment, away from direct sunlight.
Terms Lab Use Only. This information is for educational purposes only and does not constitute medical advice.

Shipping Conditions: Ambient temperature.

Please note that RAD-150 (TLB-150) was not developed by Radius Health, Inc. While the official name is TLB-150, it was coined RAD-150 due to its structural similarity to RAD-140, its parent compound.


RAD 150, also known as TLB 150, is the esterified version of the popular SARM, RAD 140. RAD 140 has been studied most thoroughly on male gonadectomized rats suffering from neurodegenerative decline due to decreased androgen levels.  


Overall, the fascinating study conducted by Jayaramen et. Al came to the conclusion that in male rats, supplementation with RAD 140 had neuroprotective effects on the brain via MAPK signaling. Additionally, the study found that treatment with RAD 140 was actually just as effective in protecting against cell death as testosterone treatment (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959610/). In addition to providing neuroprotection, testing of RAD 140 in juvenile monkeys over a 28 day period was shown to have led to an average of 10% increase in body weight. Through the use of DEXA scans it was found that the weight gain was primarily lean muscle mass.


Process of Esterification

Esterification occurs when a substitution reaction takes place. The specific substitution reaction that occurs when a compound becomes an ester, is derived from a carboxylic acid. The hydroxyl group (-OH) of the carboxylic acid is replaced with an alkyl (-O-) group. Esterification occurs when the carboxylic acid is exposed to heat and a strong acid, normally sulphuric acid. In some cases, various other strong acids such as hydrochloric acid will be used in order to catalyze the substitution reaction (https://www.chemguide.co.uk/organicprops/alcohols/esterification.html).  


Difference between RAD 140 and RAD 150 

RAD 150 is the esterified version of RAD 140. The main structural difference between the two compounds is the group of benzoate esters that were added during the substitution reaction of esterification. Adding the group of benzoate esters increases the alkalinity of the compound thus making it more stable than RAD 140 itself (https://bodyshock.pro/en/products/rad-150-60-caps-3487.html).  In order to synthesize RAD 150 from Testolone, it has to undergo the process of esterification. During the substitution reaction, a group of benzoate esters is added to Testolone in order to turn the compound into its esterified version, accounting for the main structural difference between the two compounds. By adding the benzoate ester group, the compound now has increased alkalinity, thus indicating that the esterified compound is more stable than Testolone (https://bodyshock.pro/en/products/rad-150-60-caps-3487.html).  


Additionally, in a similar fashion to other esterified SARMs, the bioavailability and the half-life of RAD 150 are increased. With increased bioavailability, the compound is absorbed much faster, and with increased half-life the compound is active for far longer than RAD 140, the nonesterified compound. This indicates that by esterifying RAD 140 there are additional potential benefits that are added. Furthermore, when comparing Testolone to RAD 150, RAD 150 is similar to other esterified SARMs with an increase in half-life and bioavailability. By increasing the half-life of RAD 150, the compound is considered active for a longer period of time than when supplementation with Testolone. Additionally, when bioavailability is increased, the compound is absorbed at a faster rate. It can be concluded that when Testolone undergoes esterification, there are several additional benefits that can be derived from the resulting compound, RAD 150. 


RAD150 compound is available in powdered and poly-cell formula.  We employ an amphiphilic copolymer to form polymeric micelles that enhance the bioavailability of select SARMs. Furthermore, our nano-emulsification process ensures minimum polymeric micelle size and variance. Most importantly, our Poly-Cell Formula TM is optimized for sublingual absorption with a minimal taste profile. This stands in contrast to PEG, which is often intolerable for sublingual delivery due to its very unpleasant taste, leading to poor compliance among research participants. 


The primary concern for SARM researchers today is where to buy SARMS that are reliable and consistently pure. Umbrella Labs insures and guarantees its product purity by incorporating a process of Independent testing using Mass Spectrometry and Ultraviolet Radiation. Certificates of our product Independent tests are posted with our product descriptions.


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*This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).




RAD-150 for sale

RAD-150 for sale

RAD 150 TLB 150 Certification of Authenticity COA 

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Additional information

Weight 4 oz
Dimensions 3 × 3 × 5 in
Formula Option

CAS Number‎

Molar Mass

497.93 g·mol−1

Molecular Formula